The article deals with simulation of visual guided robot (VGR) in offline programming software Fanuc RoboGuide. At the beginning there is a brief description of the Fanuc RoboGuide system. The practical part contains an example of the task where the configuration and demonstration of offline programming of visual guided robot system via industrial camera is presented. The main aim of the work is to practically verify the functionality of the system usable for intelligent handling and assembly workplaces.