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The results of computer simulation of thermoforming process made using ANSYS Polyflow software are presented in this paper. The analysis of the wall thickness distribution across an U-shaped thermoformed product manufactured using a positive mould was made. The simulation results were verified using a mould manufactured in a 3D printing process which was Fused Deposition Modelling (FDM) and a poly(ethylene terephthalate) formed sheet. It was proven that the computer simulation and a tool made with a Rapid Tooling technology can be useful for predicting the quality of a thermoformed part, particularly to find the problems with thin-walled areas.